Blar i forfatter "McCourt, Peter"

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    • Photonic-chip assisted correlative light and electron microscopy 

      Tinguely, Jean-Claude; Steyer, Anna Maria; Øie, Cristina Ionica; Helle, Øystein Ivar; Dullo, Firehun Tsige; Olsen, Randi; McCourt, Peter; Schwab, Yannick; Ahluwalia, Balpreet Singh (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-07)
      Correlative light and electron microscopy (CLEM) unifies the versatility of light microscopy (LM) with the high resolution of electron microscopy (EM), allowing one to zoom into the complex organization of cells. Here, we introduce photonic chip assisted CLEM, enabling multi-modal total internal reflection fluorescence (TIRF) microscopy over large field of view and high precision localization of the ...

    • The wHole Story About Fenestrations in LSEC 

      Szafranska, Karolina; Kruse, Larissa D.; Holte, Christopher Florian; McCourt, Peter; Zapotoczny, Bartlomiej (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-13)
      The porosity of liver sinusoidal endothelial cells (LSEC) ensures bidirectional passive transport of lipoproteins, drugs and solutes between the liver capillaries and the liver parenchyma. This porosity is realized via fenestrations – transcellular pores with diameters in the range of 50–300 nm – typically grouped together in sieve plates. Aging and several liver disorders severely reduce LSEC ...